| Episode credited cast: |
 | David Letterman | - | Himself - Host |
 | Sylvester Stallone | - | Himself - Guest |
 | Paul Teutul Jr. | - | Himself - Guest (as 'The Teutuls') |
 | Paul Teutul Sr. | - | Himself - Guest (as 'The Teutuls') |
 | The Mars Volta | - | Themselves - Musical Guest |
 | Paul Shaffer | - | Himself - Musical Director |
| Rest of cast listed alphabetically: |
 | Cedric Bixler-Zavala | - | Himself - The Mars Volta |
| Pat Farmer | - | Himself - Spinning the 'Late Show Prize Wheel' |
| Alan Kalter | - | Himself - Announcer |
| Omar Rodriguez-Lopez | - | Himself - The Mars Volta |
 | Bruce Willis | - | Himself - Guest |
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