Episode credited cast: |
 | David Letterman | - | Himself - Host |
 | Bill Murray | - | Himself |
 | Viva Brother | - | Themselves - Musical Guest (as Brother [UK]) |
 | Brian Miser | - | Himself - The Human Fuse |
 | Paul Shaffer | - | Himself - Musical Director |
Rest of cast listed alphabetically: |
 | Catherine Duchess of Cambridge | - | Herself - On Balcony After Wedding (archive footage) (as Kate Middleton) |
 | Dave Johnson | - | Himself - Phone Interview (voice) |
 | Alan Kalter | - | Himself - Announcer |
 | Prince William | - | Himself - On Balcony After Wedding (archive footage) (as Prince William Windsor) |