| Episode cast overview, first billed only: |
 | Piers Morgan | - | Himself - Presenter |
 | Susanna Reid | - | Herself - Presenter |
 | Ranvir Singh | - | Herself - GMB Political Editor |
 | Mark Wallace | - | Himself - ConservativeHome (as Mark Wallis) |
 | Ross King | - | Himself - LA Correspondent |
 | Simon Woolley | - | Himself - Director, Operation Black Vote |
 | Hilary Jones | - | Himself - Health Editor (as Dr Hilary Jones) |
| Simon Smith | - | Himself - Chef, Tameside Hospital |
| Angela Brierley | - | Herself - Head of Service Transformation |
| Amanda Bromley | - | Herself - HR Director, Tameside Hospital |
 | Lise McNally | - | Herself - Granada North West Newsreader |
| Justin Madders | - | Himself - Lab, Ellesmere Port and Neston (archive footage) (as Justin Madders MP) |
 | Kerrie Gosney | - | Herself - Granada North West Weather Forecaster |
 | Andrew Pierce | - | Himself - Consultant Editor, Daily Mail |
 | Kevin Maguire | - | Himself - Associate Editor, Daily Mirror |
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