Dixie Carter, being a Republican, didn't always agree with her character's Liberal views. So she and the show's producers came to an agreement: whenever Julia would go off on something, on which Dixie didn't quite agree, she got to showcase her singing in a future episode.

The exterior of Sugarbaker & Associates Interior Design is The Villa Marre, a Victorian mansion built in 1881, and located in the MacArthur Park Historic District of Little Rock, Arkansas. It is listed in the National Registry of Historic Places.

Delta Burke and Jean Smart met their husbands while working on the show.

During the first season, CBS kept moving the show around, moving it from its original Monday night time slot to Thursday, and then to Sunday. This devastated the ratings, which didn't pick up until it returned to Monday. CBS was going to cancel it, but then protests from Viewers for Quality Television convinced the network to renew it.

Despite the fact that she had already had significant roles in two prior television series, CBS was unsure about Delta Burke as one of the stars of the show, because of her beauty queen background.

Of the twenty-five series the major networks debuted in 1986, this show was the only one to still be on the air for the 1992-1993 season.

Suzanne's housekeeper, Consuela, was often talked about, but never seen on the show.

Of the original cast, Jean Smart was the only one not born in the south or southeastern United States. She was born and raised in Seattle, Washington.

Dixie Carter is the only cast member to appear in every episode.

Dixie Carter was seventeen years older than Delta Burke. It's reported in a later episode, that their mother was married to their father, they divorced, their father married again, had their brother Clayton, played by the late Lewis Grizzard, they divorced and he remarried Julia and Suzanne's mother, accounting for the age difference.

Linda Bloodworth-Thomason wrote all of her scripts on legal pads, and they would turn out longer than the average sitcom script. As a result, the network would often have to time compress parts of shows to keep from cutting key material.

In September after the DW Creator wrote an Op-Ed piece in the Hollywood Reporter, ABC decided to give Designing Women a script commitment, less then a day after Linda Thomason blasted ex-CBS boss Les Moonves (the network the show was originally on) and ABC was highly interested in rebooting the series. Jean Smart also claimed she wanted in on the reboot, as well as Annie Potts who said earlier in 2018 she'd do a reboot/revival during her spare time. The project is still in its script commitment faze.

The only Emmy nominations for acting went to Delta Burke, Meshach Taylor, and Alice Ghostley.

When Dixie Carter left the cast of Diff'rent Strokes (1978), her role of Maggie McKinney-Drummond was taken over by Mary Ann Mobley. In this show's season five opener, "A Blast from the Past", Mobley appeared as a special guest star, playing a friend of Carter's character.

The name of the show, Designing Women, is taken from an expression to describe women who are acting in a calculating, deceitful way.

The series enjoyed a 3 Year ratings high when it aired back-to-back successfully with Murphy Brown (1988).

According to creator Linda Bloodworth-Thomason during the 2006 Designing Women Reunion the character of Anthony played by Meshach Taylor was supposed to be a one off. But fans loved the character of Anthony so much that he was offered a full time role on the show. He joined the main cast officially for the second season in 1987.

During season 6, there was a story line for Mary-Jo and wanting to have a baby. Producers dropped this idea as other CBS show Murphy Brown (1988) were already doing the exact same thing with Murphy and they didn't want to copy the show.

During Season 1, the show had actually been put on hiatus and canceled at the same time. Until the now defunct Viewers for Quality TV stepped in. Over 50,000 letters were written to CBS asking them to save the show. It wasn't until February (A month after the show was canceled) was it saved. It was moved to Monday's as it couldn't compete in ratings on a Saturday with Golden Girls.

Jean Smart had decided to leave the series on her own accord, as she had grown tired of the role of Charlene. But her main reason for leaving the series was to look after her young family. Smart's final episode was the season 6 two part episode "The Big Desk" with over 30 million viewers tuning in.

Season 6 enjoyed its highest ranking of the series. Ranking 6th over 30 million people tuned in when Jean Smart's character Charlene left the show in the season 6 premiere.

Hal Holbrook character of Reece Watson was written/killed off in season 5 due to Holbrook being offered a role in Evening Shade (1990)

During Delta Burke's falling out with the ladies on the show, she privately apologized to everyone. But it took over a decade for Delta and Dixie Carter to make amends. Burke apologized to Carter (who at the time of the falling out between the two of them, sided with producers over Burke's on set behavior.) in 2002 and made an appearance on Carter's show "Family Law" and all appeared well between the 2 during the 2003 designing women reunion, and looked even better during the 2006 reunion. Burke and the ladies were heartbroken over Carter's death as well, and in one media photo Burke is seen having to be held up by husband Gerard and co-star Annie Potts.

Alice Ghostley's character of Bernice Clifton was not related to any of the characters on the show.

Despite Season 6 sitting high in the rank ratings of 6th, the show was moved to Friday nights (Or the 'Friday Night Death Slot') for season 7, effectively killing the show, it slipped from 6th to 67th and despite receiving no other competition from any other show, the show was canceled after 7 years, and the cancellation was followed with the cancellation of Major Dad (1989) and The Golden Palace (1992).