| Episode credited cast: |
 | Mike Greenberg | - | Himself - Host |
 | Mike Golic | - | Himself - Host |
| Rest of cast listed alphabetically: |
| Jake Arrieta | - | Himself - Chicago Cubs Pitcher (archive footage) |
| Kam Chancellor | - | Himself - Seattle Seahawks (archive footage) |
| Ryan Fitzpatrick | - | Himself - NFL Free Agent Quarterback (archive footage) |
 | Matt Forte | - | Himself - New York Jets (archive footage) |
| Robert Griffin III | - | Himself - NFL Free Agent Quarterback (archive footage) |
| Paul Hembekides | - | Himself - Researcher, Mike & Mike |
 | Holly Holm | - | Herself - Mixed Martial Arts Fighter (archive footage) |
 | Dwight Howard | - | Himself - Houston Rockets (archive footage) |
| Tom Izzo | - | Himself - Michigan State University Men's Basketball Coach (voice) |
| Malik Jackson | - | Himself - Jacksonville Jaguars (archive footage) |
 | Calvin Johnson | - | Himself - Retired NFL Player (archive footage) |
| Bomani Jones | - | Himself - Highly Questionable |
| Jen Lada | - | Herself - ESPN |
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