| Episode cast overview, first billed only: |
 | Piers Morgan | - | Himself - Presenter |
 | Susanna Reid | - | Herself - Presenter |
 | Laura Tobin | - | Herself - Weather Forecaster |
 | Richard Gaisford | - | Himself - Correspondent |
 | Christine Osborne | - | Herself - Mother of Darren Osborne (voice) |
 | Kate Garraway | - | Herself - Presenter |
 | Nick Dixon | - | Himself - Correspondent |
 | Chuka Umunna | - | Himself - Remain Campaigner (as Chuka Umuna MP) |
| Paul Cosford | - | Himself - Public Health England (as Professor Paul Cosford) |
 | Simon Cowell | - | Himself - Organised Charity Single |
 | Jessie J | - | Herself - Singer |
 | Robbie Williams | - | Himself - Guest |
 | Natasha Carter | - | Herself - Granada North West Newsreader |
| Charlotte Hardy | - | Herself - Olivia's Mum (as Charlotte Campbell) |
 | Amanda Houston | - | Herself - Granada North West Weather Forecaster |
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