| Episode credited cast: |
 | Christopher Timothy | - | Dr. Brendan 'Mac' McGuire (credit only) |
 | Maggie Cronin | - | Kate McGuire |
 | Corrinne Wicks | - | Dr. Helen Thompson (credit only) |
 | Tom Butcher | - | Dr. Marc Eliot |
 | Ariyon Bakare | - | Dr. Ben Kwarme (credit only) |
| Natalie J. Robb | - | Dr. Jude Carlyle |
 | Stirling Gallacher | - | Dr. Georgina Woodson (credit only) |
 | Eva Fontaine | - | Faith Walker (credit only) |
 | Diane Keen | - | Julia McGuire (credit only) |
| Rest of cast listed alphabetically: |
| Michael Beint | - | William Pennington |
 | David Burke | - | Martin Shepley |
| Emma Fildes | - | Debbie McQueen |
 | Fiona Gillies | - | Georgia Pennington |
| Sean Gleeson | - | Ronnie Woodson |
| Snow Hsu | - | Anna Mae Pennington |
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