| Episode cast overview, first billed only: |
 | Andrew Lancel | - | Dr. Andrew Collin |
 | Helen Baxendale | - | Dr. Claire Maitland |
 | Jonathan Dow | - | Dr. James Mortimer (as Jo Dow) |
 | Peter O'Brien | - | Mr. Cyril 'Scissors' Smedley |
 | Ace Bhatti | - | Dr. Rajesh Rajah (as Ahsen Bhatti) |
| Tom Watson | - | Mr. Ernest Docherty |
| Michael MacKenzie | - | Dr. Graham Turner |
| Jack Fortune | - | Mr. Adrian DeVries |
 | Fred Pearson | - | Dr. Barry Yates |
| Peter Biddle | - | CN Patrick Garden |
 | Nisha Nayar | - | Nasreen (as Nisha K. Nayar) |
| Joyce Falconer | - | SN Tricia 'Whitecoat' Williams |
| Marc Anwar | - | 1st Heavy (as Omar Salimi) |
| Andrew Clover | - | Dr. Phil Kirkby |
| Nicholas Palliser | - | Mr. Tennant |
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