| Episode cast overview, first billed only: |
 | Matthias Schloo | - | Polizeikommissar Mattes Seeler |
 | Sanna Englund | - | Polizeioberkommissarin Melanie Hansen |
| Gerit Kling | - | Dr. Jasmin Jonas |
| Serhat Çokgezen | - | Polizeimeister Tarik Coban (as Serhat Cokgezen) |
| Janette Rauch | - | Polizeihauptmeisterin Claudia Fischer |
| Rhea Harder | - | Polizeiobermeisterin Franziska 'Franzi' Jung |
| Bruno F. Apitz | - | Polizeihauptkommissar Hans Moor |
 | Dietrich Adam | - | Peter Gerold |
 | Simon Böer | - | Dr. Philipp Rost |
| Dorka Gryllus | - | Ilona Herwig |
| Peer Jäger | - | Polizeioberrat Martin Berger |
 | Harald Maack | - | Polizeioberkommissar Jörn 'Wolle' Wollenberger |
| Christoph Michel | - | Rainer Voss |
 | Oana Solomon | - | Paulina Kowalczyk |
| Tim Morten Uhlenbrock | | |
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