| Cast overview: |
 | Anasthasie Tudieshe | - | Narrator (voice) |
| Simon Backès | - | William S. Burroughs (voice) |
| Damien Boisseau | - | Allen Ginsberg (voice) |
| Eric Herson-Macarel | - | Jack Kerouac (voice) |
 | Jack Kerouac | - | Himself (archive footage) |
 | Allen Ginsberg | - | Himself (archive footage) |
 | William S. Burroughs | - | Himself (archive footage) |
 | J. Edgar Hoover | - | Himself (archive footage) |
| Jean-Jacques Lebel | - | Himself (archive footage) |
| Gregory Corso | - | Himself (archive footage) |
 | Louis-Ferdinand Céline | - | Himself (archive footage) (as Céline Destouches) |
 | Bob Dylan | - | Himself (archive footage) |
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