Симпсоны Brother's Little Helper (1989– ) watch online HD

The episode title is a play on "Mother's Little Helper", a song by The Rolling Stones, which in turn is a euphemism for certain prescription drugs believed to be commonly used (or abused) by middle-class women in the US and UK in the 1960s (such as barbiturate sleeping pills, amphetamine diet pills, and benzodiazepine tranquilizers).

Homer says that Bart "has gone from Goofus to Gallant", a reference to the comic strip "Goofus and Gallant", which appeared in 'Highlights', a magazine for children. Typically, Goofus would do something rude or destructive, while Gallant served as an example of proper behavior.

At the very end Bart sings about his drugs using the Popeye theme tune. Nancy Cartwright who voices Bart, was also the voice of Woody on Popeye and Son.

Bart is shown reading a book called 'The 7 Habits of Highly Effective Pre-Teens' and gives a copy of 'Chicken Soup for the Loser' to Homer. These are plays on the real books 'The 7 Habits of Highly Effective People' and 'Chicken Soup for the Soul' (both of which produced multiple sequels and spin-offs).

The Terminal Man (1974) is an influence behind (#11.2).

The drug company that produces the fictitious drug Focasyn is called "The Pharm Team", a pun on "farm team", a team used to groom players for a professional sports team. For example, baseball in the United States has an extensive farm team system.

L'uomo terminale (1974) is considered an influence behind (#11.12). In the film, George Segal stars as a epileptic man whom is implanted with a experimental microchip in his brain that control him when he suffers violent seizures which he soon goes out of control and becomes addicted to the electrical impulses which turns him into a violent man. In (#11.12) Bart takes an untested new behavioral medicine called Focusyn to improve his behavior when he is diagnosed with ADHD. But, Bart soon begins suffering from drug psychosis and paranoia and refuses to go off the Focusyn which he flees and embarks on a swath of destruction.

A scene in the episode shows Marge standing in front of the tank Bart has stolen. The scene is a reference to Tank Man, the anonymous man who stood in the way of a column of tanks the morning after the Chinese military forcibly removed pro-democracy protesters from Beijing's Tiananmen Square.

Blackboard: "Pork is not a verb".

Couch: The Simpsons are blank paint-by-numbers figures; Asian animators come in and color the family, but do not detail their eyes.

Hosey the Bear, which can be seen in the beginning of the episode, is a reference to the United States Forest Service's mascot Smokey Bear.

After Bart has flooded the school gym, Skinner can be seen wiping mud off his eyes in an homage to American actor Oliver Hardy.

The sequence of Bart stealing an army tank and destroying half of Springfield under the influence of mind-altering substances is likely a reference to Shawn Nelson, a man infamous for a similar, albeit serious, incident.

Bart's line, "Cost of paper, 5 cents. Cost of a mother's love, priceless," echoes dialogue from a MasterCard commercial.

Springfield's Fort Fragg is a parody of Fort Bragg (military installation).

Homer is going to ask his electronic organizer how many leagues are in a furlong, the answer is 0.036207