| Cast overview, first billed only: |
 | Moses Gurman | - | Shelton Durge |
| Julie Harris | - | Castor |
| Joe Higgs | - | Riley Tompkins Sr. (as J.P. Higgs) |
 | Mackie Lou Vigal | - | Dr. Kazzan (as Mackie-Lou Vigal) |
| Eric Powell | - | Lab Assistant |
 | Robyn Wyrick | - | Torture Victim 1 |
| Jennifer Shea | - | Lab Victim 1 |
| Jeff Poch | - | Lab Victim 2 |
| David Murnan | - | Support Group Member 1 |
| LaShon Perkins | - | Support Group Member 2 |
| Jillian Carnick | - | Support Group Member 3 |
| Andrew Bennett | - | Mongo |
| Traci Poles | - | Past Support Group Member 1 |
| Emma Tucker | - | Past Support Group Member 2 |
| Jennifer Wyrick | - | Past Support Group Member 3 |
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