| Episode cast overview, first billed only: |
 | James Pritchett | - | Dr. Matt Powers |
| Elizabeth Hubbard | - | Dr. Althea Davis |
| Gerald Gordon | - | Dr. Nick Bellini |
| Lydia Bruce | - | Dr. Maggie Powers (credit only) |
| David O'Brien | - | Dr. Steve Aldrich (credit only) |
| Carolee Campbell | - | Nurse Carolee Simpson (credit only) |
| Sally Gracie | - | Martha Allen (credit only) |
| Palmer Deane | - | Dr. Hank Iverson (credit only) |
| Anna Stuart | - | Toni Ferra |
| Geraldine Court | - | Dr. Ann Larimer (credit only) |
 | Armand Assante | - | Dr. Michael Powers |
| Elizabeth Lawrence | - | Virginia Dancy |
| Jonathan Hogan | - | Jerry Dancy |
 | Julia Duffy | - | Penny Davis (credit only) |
 | David Elliott | - | Billy Aldrich (as David Michael Elliott) (credit only) |
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