| Episode cast overview, first billed only: |
 | Kris Aquino | - | Celine Crisanto |
 | Gabby Concepcion | - | Steve Sebastian |
 | Albert Martinez | - | Frank Crisanto |
 | Gina Pareño | - | Petulah Crisanto |
 | Ronaldo Valdez | - | Supremo / Rustico Crisanto |
 | Jaclyn Jose | - | Astrud Quijano |
 | Max Eigenmann | - | Alicia Perez |
 | Maricar Reyes | - | Celina Castillo-Sebastian |
 | Coco Martin | - | Ringgo Quijano Crisanto |
 | Gerald Anderson | - | Robbie Castillo |
 | Kim Chiu | - | Gwen Crisanto |
 | James Bimby Aquino | - | Michael Crisanto (as Baby James Yap) |
 | Pooh | - | Barry (as Reynaldo 'Pooh' Garcia) |
 | Jhong Hilario | - | Jason |
 | Bing Davao | - | Matt Cordero |
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