| Episode credited cast: |
 | Mike Greenberg | - | Himself - Co-Host |
 | Mike Golic | - | Himself - Co-Host |
| Rest of cast listed alphabetically: |
 | Kareem Abdul-Jabbar | - | Himself - Basketball Hall of Famer |
| Brian Billick | - | Himself - Analyst, NFL Network (voice) |
 | Tom Brady | - | Himself - New England Patriots Quarterback (archive footage) |
| Terry Collins | - | Himself - New York Mets Manager (archive footage) |
 | Bradley Cooper | - | Himself - Actor (voice) |
| Johnny Cueto | - | Himself - Kansas City Royals Pitcher (archive footage) |
| Ron Darling | - | Himself - Former Baseball Pitcher (voice) |
| Jacob deGrom | - | Himself - New York Mets Pitcher (archive footage) |
| Jerry Kill | - | Himself - Former University of Minnesota Men's Baskteball Coach (archive footage) |
| Andrew Luck | - | Himself - Indianapolis Colts Quarterback (archive footage) |
 | Peyton Manning | - | Himself - Denver Broncos Quarterback (archive footage) |
| Nick Rago | - | Himself - Social Media Producer, Mike & Mike (as Nick/Nate) |
| Jayson Stark | - | Himself - ESPN MLB Insider (voice) |
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