| Episode cast overview, first billed only: |
 | Thomas Scharff | - | Polizeihauptkommissar Nils Meermann |
 | Sanna Englund | - | Polizeioberkommissarin Melanie Hansen |
 | Frank Vockroth | - | Polizeioberkommissar Bernd 'Boje' Thomforde |
| Rhea Harder | - | Polizeimeisterin Franziska 'Franzi' Jung |
| Peer Jäger | - | Polizeioberrat Martin Berger |
 | Harald Maack | - | Polizeioberkommissar Jörn 'Wolle' Wollenberger |
| Marie-Lou Sellem | - | Dr. Anna Jacobi |
| Fabian Harloff | - | Dr. Philipp Haase |
| Maike Bollow | - | Dr. Juliane Dietrich |
| Gerit Kling | - | Dr. Jasmin Jonas |
 | Wolf Roth | - | Lucky Böhme |
| Arnfried Lerche | - | Werner Hertel |
| Hendrik Arnst | - | Didi Esser |
| Dagmar Leesch | - | Nadja Ortmann |
| Traudel Sperber | - | Chris Hartel |
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