| Episode cast overview, first billed only: |
 | Dieter Bellmann | - | Prof. Gernot Simoni |
| Thomas Rühmann | - | Dr. Roland Heilmann |
| Hendrikje Fitz | - | Pia Heilmann |
| Johannes Steck | - | Dr. Achim Kreutzer |
| Andrea Kathrin Loewig | - | Dr. Kathrin Globisch |
| Alexa Maria Surholt | - | Sarah Marquardt |
| Jutta Kammann | - | Ingrid Rischke (credit only) |
 | Fred Delmare | - | Opa Friedrich (credit only) |
 | Ursula Karusseit | - | Charlotte Gauss (credit only) |
| Cheryl Shepard | - | Dr. Elena Eichhorn |
| Thomas Koch | - | Dr. Philipp Brentano |
| Arzu Bazman | - | Arzu Ritter |
| Stephen Dürr | - | Vladi Nemetz (credit only) |
 | Uta Schorn | - | Barbara Grigoleit (credit only) |
| Maren Gilzer | - | Yvonne Habermann |
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